PLOS

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PLOS ONE
TITLE

Definition and Classification for Adverse Events Following Spinal and Peripheral Joint Manipulation and Mobilization: A Scoping Review

98 Studies Reviewed

SOURCE

REFERENCE
3
NICE
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123

organisation

PLOS ONE

TITLE

Definition and Classification for Adverse Events Following Spinal and Peripheral Joint Manipulation and Mobilization: A Scoping Review

98 Studies Reviewed

SOURCE

This scoping review examined how adverse events after spinal and joint manipulation have been defined and classified in the literature, drawing on 98 studies published between 1993 and 2021, focused on consistency in terminology rather than how often events occur.

What was studied?

The review checked whether 98 studies on manipulation and mobilisation agreed on a definition of an adverse event and how to classify its severity, rather than measuring how often such events actually happened.

What did they find?

There is no agreed standard for defining an adverse event: 69 of the 98 studies gave a direct definition, 29 only implied one, and severity classification varied widely. The review concluded that clearer, more consistent reporting standards are needed.

Why it matters

Safety figures quoted from one study do not always mean the same thing as those from another, since definitions differ so widely. Comparing risk statistics directly can be misleading without checking what each study counted.

Why we included it

It illustrates a wider theme: safety statistics are not automatically comparable across studies, which is why individual risks and benefits are best discussed in person rather than reduced to one quoted figure.