SPINE J

organisation

The Spine Journal
TITLE

Chiropractic Manipulation in the Treatment of Acute Back Pain and Sciatica with Disc Protrusion: A Randomized Double-Blind Clinical Trial of Active and Simulated Spinal Manipulations

55% vs 20% Leg Pain Resolved

SOURCE

REFERENCE
73
NICE
REFERENCE
123

organisation

The Spine Journal

TITLE

Chiropractic Manipulation in the Treatment of Acute Back Pain and Sciatica with Disc Protrusion: A Randomized Double-Blind Clinical Trial of Active and Simulated Spinal Manipulations

55% vs 20% Leg Pain Resolved

SOURCE

This randomised, double-blind trial compared real spinal manipulation against a simulated, sham manipulation in 102 patients with acute low back pain and sciatica confirmed on MRI to be caused by a disc protrusion, measuring pain relief and medication use.

What was studied?

The trial followed 102 patients, average age 43.1, tracking how many became completely pain-free, how many saw radiating leg pain disappear entirely, and total days of pain and medication use, comparing follow-up scans of the disc.

What did they find?

28% of the real-manipulation group became completely pain-free compared with 6% of the sham group, and 55% saw radiating leg pain disappear entirely compared with 20%. No adverse events occurred in either group, and the disc protrusion looked unchanged on follow-up scans in both.

Why it matters

This shows manipulation can meaningfully help even when there's a confirmed disc protrusion on imaging, something often mistakenly seen as a reason to avoid manipulation altogether. The improvement happened without the disc physically changing shape.

Why we included it

It illustrates that imaging findings and treatment decisions aren't the same thing: a structural finding on a scan doesn't automatically dictate which treatments can help, since the body can respond well without the structure changing.